Cargando…
Succinate dehydrogenase subunit B inhibits the AMPK-HIF-1α pathway in human ovarian cancer in vitro
BACKGROUND: Ovarian carcinoma is one of the most common gynecological cancers with high mortality rates. Numerous evidences demonstrate that cancer cells undergo metabolic abnormality during tumorigenesis in tumor microenvironment and further facilitate tumor progression. Succinate dehydrogenase (SD...
Autores principales: | Chen, Lilan, Liu, Ting, Zhang, Shu, Zhou, Jinhua, Wang, Yunfei, Di, Wen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279696/ https://www.ncbi.nlm.nih.gov/pubmed/25491408 http://dx.doi.org/10.1186/s13048-014-0115-1 |
Ejemplares similares
-
Hereditary Pheochromocytoma With a Mutation in the Succinate Dehydrogenase Subunit A Gene
por: Karuppasamy, Gowri, et al.
Publicado: (2022) -
Succinate dehydrogenase variants in paraganglioma: why are B subunit variants ‘bad’?
por: Gruber, Lucinda M, et al.
Publicado: (2023) -
Predicted Succinated Dehydrogenase Subunit Variant Pathogenicity: Why Are SDHB Variants “Bad”?
por: Gruber, Lucinda, et al.
Publicado: (2021) -
Alternative splicing isoform in succinate dehydrogenase complex, subunit C causes downregulation of succinate-coenzyme Q oxidoreductase activity in mitochondria
por: SATOH, NANA, et al.
Publicado: (2015) -
Inhibition of Succinate Dehydrogenase by Pesticides (SDHIs) and Energy Metabolism
por: Bouillaud, Frederic
Publicado: (2023)