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Prioritizing causal disease genes using unbiased genomic features

BACKGROUND: Cardiovascular disease (CVD) is the leading cause of death in the developed world. Human genetic studies, including genome-wide sequencing and SNP-array approaches, promise to reveal disease genes and mechanisms representing new therapeutic targets. In practice, however, identification o...

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Detalles Bibliográficos
Autores principales: Deo, Rahul C, Musso, Gabriel, Tasan, Murat, Tang, Paul, Poon, Annie, Yuan, Christiana, Felix, Janine F, Vasan, Ramachandran S, Beroukhim, Rameen, De Marco, Teresa, Kwok, Pui-Yan, MacRae, Calum A, Roth, Frederick P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279789/
https://www.ncbi.nlm.nih.gov/pubmed/25633252
http://dx.doi.org/10.1186/s13059-014-0534-8