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Prioritizing causal disease genes using unbiased genomic features
BACKGROUND: Cardiovascular disease (CVD) is the leading cause of death in the developed world. Human genetic studies, including genome-wide sequencing and SNP-array approaches, promise to reveal disease genes and mechanisms representing new therapeutic targets. In practice, however, identification o...
Autores principales: | Deo, Rahul C, Musso, Gabriel, Tasan, Murat, Tang, Paul, Poon, Annie, Yuan, Christiana, Felix, Janine F, Vasan, Ramachandran S, Beroukhim, Rameen, De Marco, Teresa, Kwok, Pui-Yan, MacRae, Calum A, Roth, Frederick P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279789/ https://www.ncbi.nlm.nih.gov/pubmed/25633252 http://dx.doi.org/10.1186/s13059-014-0534-8 |
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