Familial Lymphoproliferative Malignancies and Tandem Duplication of NF1 Gene

Background. Neurofibromatosis type 1 is a genetic disorder caused by loss-of-function mutations in a tumor suppressor gene (NF1) which codifies the protein neurofibromin. The frequent genetic alterations that modify neurofibromin function are deletions and insertions. Duplications are rare and pheno...

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Detalles Bibliográficos
Autores principales: Fernandes, Gustavo, Souto, Mirela, Costa, Frederico, Oliveira, Edite, Garicochea, Bernardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279825/
https://www.ncbi.nlm.nih.gov/pubmed/25580325
http://dx.doi.org/10.1155/2014/685857

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279825/
https://www.ncbi.nlm.nih.gov/pubmed/25580325
http://dx.doi.org/10.1155/2014/685857

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