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The Structure of Cross‐β Tapes and Tubes Formed by an Octapeptide, αSβ1

Elaborate morphology: The αSβ1 peptide, a fragment of α‐synuclein, assembles into flat tapes consisting of a peptide bilayer, which can be modeled based on the cross‐β structure found in amyloid proteins. The tapes are stabilized by hydrogen bonding, whilst the amphiphilic nature of the peptide resu...

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Detalles Bibliográficos
Autores principales: Morris, Kyle L., Zibaee, Shahin, Chen, Lin, Goedert, Michel, Sikorski, Pawel, Serpell, Louise C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY‐VCH Verlag 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279883/
https://www.ncbi.nlm.nih.gov/pubmed/23307646
http://dx.doi.org/10.1002/anie.201207699