Checkpoint Blockade Cancer Immunotherapy Targets Tumour-Specific Mutant Antigens

The immune system plays key roles in determining the fate of developing cancers by not only functioning as a tumour promoter facilitating cellular transformation, promoting tumour growth and sculpting tumour cell immunogenicity(1–6), but also as an extrinsic tumour suppressor that either destroys de...

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Detalles Bibliográficos
Autores principales: Gubin, Matthew M., Zhang, Xiuli, Schuster, Heiko, Caron, Etienne, Ward, Jeffrey P., Noguchi, Takuro, Ivanova, Yulia, Hundal, Jasreet, Arthur, Cora D., Krebber, Willem-Jan, Mulder, Gwenn E., Toebes, Mireille, Vesely, Matthew D., Lam, Samuel S.K., Korman, Alan J., Allison, James P., Freeman, Gordon J., Sharpe, Arlene H., Pearce, Erika L., Schumacher, Ton N., Aebersold, Ruedi, Rammensee, Hans-Georg, Melief, Cornelis J. M., Mardis, Elaine R., Gillanders, William E., Artyomov, Maxim N., Schreiber, Robert D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279952/
https://www.ncbi.nlm.nih.gov/pubmed/25428507
http://dx.doi.org/10.1038/nature13988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279952/
https://www.ncbi.nlm.nih.gov/pubmed/25428507
http://dx.doi.org/10.1038/nature13988

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