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The overexpression of genes of thiol metabolism contribute to drug resistance in clinical isolates of visceral leishmaniasis (kala azar) in India

BACKGROUND: Visceral leishmaniasis (VL), also called Kala Azar (KA) or black fever in India, claims around 20,000 lives every year. Chemotherapy remains one of the most important tools in the control of VL. Current chemotherapy for Kala Azar in India relies on a rather limited arsenal of drugs inclu...

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Detalles Bibliográficos
Autores principales: Singh, Neeloo, Chatterjee, Mitali, Sundar, Shyam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280036/
https://www.ncbi.nlm.nih.gov/pubmed/25515494
http://dx.doi.org/10.1186/s13071-014-0596-1