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In vitro histone lysine methylation by NSD1, NSD2/MMSET/WHSC1 and NSD3/WHSC1L

BACKGROUND: Histone lysine methylation has a pivotal role in regulating the chromatin. Histone modifiers, including histone methyl transferases (HMTases), have clear roles in human carcinogenesis but the extent of their functions and regulation are not well understood. The NSD family of HMTases comp...

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Detalles Bibliográficos
Autores principales: Morishita, Masayo, Mevius, Damiaan, di Luccio, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280037/
https://www.ncbi.nlm.nih.gov/pubmed/25494638
http://dx.doi.org/10.1186/s12900-014-0025-x