Cargando…

Reassessing target antigens for adoptive T cell therapy

Adoptive T cell therapy can target and kill widespread malignant cells thereby inducing durable clinical responses in melanoma and selected other malignances. However, many commonly targeted tumor antigens are also expressed by healthy tissues, and T cells do not distinguish between benign and malig...

Descripción completa

Detalles Bibliográficos
Autores principales: Hinrichs, Christian S., Restifo, Nicholas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280065/
https://www.ncbi.nlm.nih.gov/pubmed/24142051
http://dx.doi.org/10.1038/nbt.2725