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Reassessing target antigens for adoptive T cell therapy
Adoptive T cell therapy can target and kill widespread malignant cells thereby inducing durable clinical responses in melanoma and selected other malignances. However, many commonly targeted tumor antigens are also expressed by healthy tissues, and T cells do not distinguish between benign and malig...
Autores principales: | Hinrichs, Christian S., Restifo, Nicholas P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280065/ https://www.ncbi.nlm.nih.gov/pubmed/24142051 http://dx.doi.org/10.1038/nbt.2725 |
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