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Novel PDE4 Inhibitors Derived from Chinese Medicine Forsythia

Cyclic adenosine monophosphate (cAMP) is a crucial intracellular second messenger molecule that converts extracellular molecules to intracellular signal transduction pathways generating cell- and stimulus-specific effects. Importantly, specific phosphodiesterase (PDE) subtypes control the amplitude...

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Detalles Bibliográficos
Autores principales: Coon, Tiffany A., McKelvey, Alison C., Weathington, Nate M., Birru, Rahel L., Lear, Travis, Leikauf, George D., Chen, Bill B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280171/
https://www.ncbi.nlm.nih.gov/pubmed/25549252
http://dx.doi.org/10.1371/journal.pone.0115937