Activation of the RhoB Signaling Pathway by Thyroid Hormone Receptor β in Thyroid Cancer Cells

Thyroid hormone receptor (TR) mediates the crucial effects of the thyroid hormone (T3) on cellular growth, development, and differentiation. Decreased expression or inactivating somatic mutations of TRs have been found in human cancers of the liver, breast, lung, and thyroid. The mechanisms of TR-as...

Descripción completa

Detalles Bibliográficos
Autores principales: Ichijo, Sayaka, Furuya, Fumihiko, Shimura, Hiroki, Hayashi, Yoshitaka, Takahashi, Kazuya, Ohta, Kazuyasu, Kobayashi, Tetsuro, Kitamura, Kenichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280201/
https://www.ncbi.nlm.nih.gov/pubmed/25548921
http://dx.doi.org/10.1371/journal.pone.0116252