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Fibronectin Matrix Formation is a Prerequisite for Colonization of Kidney Tumor Cells in Fibrin

Fibrin plays an important role in lung metastasis. Here we show that fibrin promotes colony formation in primary kidney tumor cells from patients with kidney metastasis. In addition, we found that inhibition of fibrin formation with the thrombin inhibitor hirudin in nude mice in vivo significantly r...

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Detalles Bibliográficos
Autores principales: Knowles, Lynn M., Gurski, Lisa A., Maranchie, Jodi K., Pilch, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280391/
https://www.ncbi.nlm.nih.gov/pubmed/25561973
http://dx.doi.org/10.7150/jca.10496