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Effects of simvastatin on cell viability and proinflammatory pathways in lung adenocarcinoma cells exposed to hydrogen peroxide

Lung cancer is characterized by a high mortality rate probably attributable to early metastasis. Oxidative stress is involved in development and progression of lung cancer, through cellular and molecular mechanisms which at least in part overlap with proinflammatory pathways. Simvastatin is a statin...

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Detalles Bibliográficos
Autores principales: Gallelli, Luca, Falcone, Daniela, Scaramuzzino, Monica, Pelaia, Girolamo, D’Agostino, Bruno, Mesuraca, Maria, Terracciano, Rosa, Spaziano, Giuseppe, Maselli, Rosario, Navarra, Michele, Savino, Rocco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280703/
https://www.ncbi.nlm.nih.gov/pubmed/25432084
http://dx.doi.org/10.1186/2050-6511-15-67