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Assurance calculations for planning clinical trials with time-to-event outcomes

We consider the use of the assurance method in clinical trial planning. In the assurance method, which is an alternative to a power calculation, we calculate the probability of a clinical trial resulting in a successful outcome, via eliciting a prior probability distribution about the relevant treat...

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Detalles Bibliográficos
Autores principales: Ren, Shijie, Oakley, Jeremy E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280895/
https://www.ncbi.nlm.nih.gov/pubmed/23861270
http://dx.doi.org/10.1002/sim.5916