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Antitumor effects of a dual cancer-specific oncolytic adenovirus on colorectal cancer in vitro and in vivo

The efficacy and specificity of treatment are major challenges for cancer gene therapy. Oncolytic virotherapy is an attractive drug delivery platform for cancer gene therapy. In the present study, the dual-specific antitumor oncolytic adenovirus, Ad-Apoptin-hTERT-E1a, was used to infect SW1116 human...

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Detalles Bibliográficos
Autores principales: YANG, GUOHUA, MENG, XIANGWEI, SUN, LILI, HU, NINGNING, JIANG, SHUANG, SHENG, YUAN, CHEN, ZHIFEI, ZHOU, YE, CHEN, DEXING, LI, XIAO, JIN, NINGYI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280958/
https://www.ncbi.nlm.nih.gov/pubmed/25574193
http://dx.doi.org/10.3892/etm.2014.2086