Tau Reduction Diminishes Spatial Learning and Memory Deficits after Mild Repetitive Traumatic Brain Injury in Mice

OBJECTIVE: Because reduction of the microtubule-associated protein Tau has beneficial effects in mouse models of Alzheimer's disease and epilepsy, we wanted to determine whether this strategy can also improve the outcome of mild traumatic brain injury (TBI). METHODS: We adapted a mild frontal i...

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Detalles Bibliográficos
Autores principales: Cheng, Jason S., Craft, Ryan, Yu, Gui-Qiu, Ho, Kaitlyn, Wang, Xin, Mohan, Geetha, Mangnitsky, Sergey, Ponnusamy, Ravikumar, Mucke, Lennart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281043/
https://www.ncbi.nlm.nih.gov/pubmed/25551452
http://dx.doi.org/10.1371/journal.pone.0115765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281043/
https://www.ncbi.nlm.nih.gov/pubmed/25551452
http://dx.doi.org/10.1371/journal.pone.0115765

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