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Autophagy Activation Is Involved in 3,4-Methylenedioxymethamphetamine (‘Ecstasy’)—Induced Neurotoxicity in Cultured Cortical Neurons

Autophagic (type II) cell death, characterized by the massive accumulation of autophagic vacuoles in the cytoplasm of cells, has been suggested to play pathogenetic roles in cerebral ischemia, brain trauma, and neurodegenerative disorders. 3,4-Methylenedioxymethamphetamine (MDMA or ecstasy) is an il...

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Detalles Bibliográficos
Autores principales: Li, I-Hsun, Ma, Kuo-Hsing, Weng, Shao-Ju, Huang, Shiang-Suo, Liang, Chang-Min, Huang, Yuahn-Sieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281065/
https://www.ncbi.nlm.nih.gov/pubmed/25551657
http://dx.doi.org/10.1371/journal.pone.0116565