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Synthesis and κ-Opioid Receptor Activity of Furan-Substituted Salvinorin A Analogues
[Image: see text] The neoclerodane diterpene salvinorin A, found in the leaves of Salvia divinorum, is a potent κ-opioid receptor agonist, making it an attractive scaffold for development into a treatment for substance abuse. Although several successful semisynthetic studies have been performed to e...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281103/ https://www.ncbi.nlm.nih.gov/pubmed/25426797 http://dx.doi.org/10.1021/jm501521d |