Induction of Cytomegalovirus-Specific T Cell Responses in Healthy Volunteers and Allogeneic Stem Cell Recipients Using Vaccination With Messenger RNA–Transfected Dendritic Cells

BACKGROUND: Infection with human cytomegalovirus (CMV) is a significant cause of morbidity and mortality in solid organ and hematopoietic stem cell transplant (HSCT) recipients. METHODS: The present study explored the safety, feasibility, and immunogenicity of CMV pp65 messenger RNA–loaded autologou...

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Detalles Bibliográficos
Autores principales: Van Craenenbroeck, Amaryllis H., Smits, Evelien L.J., Anguille, Sébastien, Van de Velde, Ann, Stein, Barbara, Braeckman, Tessa, Van Camp, Kirsten, Nijs, Griet, Ieven, Margareta, Goossens, Herman, Berneman, Zwi N., Van Tendeloo, Viggo F.I., Verpooten, Gert A., Van Damme, Pierre, Cools, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2015
Materias:
Clinical Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281162/
https://www.ncbi.nlm.nih.gov/pubmed/25050468
http://dx.doi.org/10.1097/TP.0000000000000272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281162/
https://www.ncbi.nlm.nih.gov/pubmed/25050468
http://dx.doi.org/10.1097/TP.0000000000000272

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