Identification of nuclear hormone receptor pathways causing insulin resistance by transcriptional and epigenomic analysis

Insulin resistance is a sine qua non of Type 2 diabetes (T2D) and a frequent complication of multiple clinical conditions, including obesity, aging, and steroid use, among others. How such a panoply of insults can result in a common phenotype is incompletely understood. Furthermore, very little is k...

Descripción completa

Detalles Bibliográficos
Autores principales: Kang, Sona, Tsai, Linus T., Zhou, Yiming, Evertts, Adam, Xu, Su, Griffin, Michael J., Issner, Robbyn, Whitton, Holly J., Garcia, Benjamin A., Epstein, Charles B., Mikkelsen, Tarjei S., Rosen, Evan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281178/
https://www.ncbi.nlm.nih.gov/pubmed/25503565
http://dx.doi.org/10.1038/ncb3080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281178/
https://www.ncbi.nlm.nih.gov/pubmed/25503565
http://dx.doi.org/10.1038/ncb3080

Ejemplares similares