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Focal Chromosomal Copy Number Aberrations Identify CMTM8 and GPR177 as New Candidate Driver Genes in Osteosarcoma

Osteosarcoma is an aggressive bone tumor that preferentially develops in adolescents. The tumor is characterized by an abundance of genomic aberrations, which hampers the identification of the driver genes involved in osteosarcoma tumorigenesis. Our study aims to identify these genes by the investig...

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Detalles Bibliográficos
Autores principales: Both, Joeri, Krijgsman, Oscar, Bras, Johannes, Schaap, Gerard R., Baas, Frank, Ylstra, Bauke, Hulsebos, Theo J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281204/
https://www.ncbi.nlm.nih.gov/pubmed/25551557
http://dx.doi.org/10.1371/journal.pone.0115835