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Granulocyte Colony-Stimulating Factor Reduces Fibrosis in a Mouse Model of Chronic Pancreatitis

BACKGROUND: Chronic pancreatitis (CP) is a necroinflammatory process resulting in extensive pancreatic fibrosis. Granulocyte colony-stimulating factor (G-CSF), a hematopoietic stem cell mobilizer, has been shown to exert an anti-fibrotic effect partly through the enrichment of bone marrow (BM) cells...

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Detalles Bibliográficos
Autores principales: Lin, Wey-Ran, Yen, Tzung-Hai, Lim, Siew-Na, Perng, Ming-Der, Lin, Chun-Yen, Su, Ming-Yo, Yeh, Chau-Ting, Chiu, Cheng-Tang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281240/
https://www.ncbi.nlm.nih.gov/pubmed/25551560
http://dx.doi.org/10.1371/journal.pone.0116229