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Optimal design of non-equilibrium experiments for genetic network interrogation

Many experimental systems in biology, especially synthetic gene networks, are amenable to perturbations that are controlled by the experimenter. We developed an optimal design algorithm that calculates optimal observation times in conjunction with optimal experimental perturbations in order to maxim...

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Detalles Bibliográficos
Autores principales: Adoteye, Kaska, Banks, H.T., Flores, Kevin B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281269/
https://www.ncbi.nlm.nih.gov/pubmed/25558126
http://dx.doi.org/10.1016/j.aml.2014.09.013