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Optimal design of non-equilibrium experiments for genetic network interrogation
Many experimental systems in biology, especially synthetic gene networks, are amenable to perturbations that are controlled by the experimenter. We developed an optimal design algorithm that calculates optimal observation times in conjunction with optimal experimental perturbations in order to maxim...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281269/ https://www.ncbi.nlm.nih.gov/pubmed/25558126 http://dx.doi.org/10.1016/j.aml.2014.09.013 |