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Apolipoprotein L1 gene variants associate with prevalent kidney but not prevalent cardiovascular disease in the Systolic Blood Pressure Intervention Trial

Apolipoprotein L1 gene (APOL1) G1 and G2 coding variants are strongly associated with chronic kidney disease (CKD) in African Americans. Here APOL1 association was tested with baseline estimated glomerular filtration rate (eGFR), urine albumin:creatinine ratio (UACR), and prevalent cardiovascular di...

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Detalles Bibliográficos
Autores principales: Langefeld, Carl D., Divers, Jasmin, Pajewski, Nicholas M., Hawfield, Amret T., Reboussin, David M., Bild, Diane E., Kaysen, George A., Kimmel, Paul L., Raj, Dominic, Ricardo, Ana C., Wright, Jackson T., Sedor, John R., Rocco, Michael V., Freedman, Barry I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281289/
https://www.ncbi.nlm.nih.gov/pubmed/25029429
http://dx.doi.org/10.1038/ki.2014.254