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Developmental regulation of human cortex transcription and its clinical relevance at base resolution

Transcriptome analysis of human brain provides fundamental insight about development and disease, but largely relies on existing annotation. We sequenced transcriptomes of 72 prefrontal cortex samples across six life stages, and identified 50,650 differentially expression regions (DERs) associated w...

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Detalles Bibliográficos
Autores principales: Jaffe, Andrew E., Shin, Jooheon, Collado-Torres, Leonardo, Leek, Jeffrey T., Tao, Ran, Li, Chao, Gao, Yuan, Jia, Yankai, Maher, Brady J., Hyde, Thomas M., Kleinman, Joel E., Weinberger, Daniel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281298/
https://www.ncbi.nlm.nih.gov/pubmed/25501035
http://dx.doi.org/10.1038/nn.3898