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Developmental regulation of human cortex transcription and its clinical relevance at base resolution
Transcriptome analysis of human brain provides fundamental insight about development and disease, but largely relies on existing annotation. We sequenced transcriptomes of 72 prefrontal cortex samples across six life stages, and identified 50,650 differentially expression regions (DERs) associated w...
Autores principales: | Jaffe, Andrew E., Shin, Jooheon, Collado-Torres, Leonardo, Leek, Jeffrey T., Tao, Ran, Li, Chao, Gao, Yuan, Jia, Yankai, Maher, Brady J., Hyde, Thomas M., Kleinman, Joel E., Weinberger, Daniel R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281298/ https://www.ncbi.nlm.nih.gov/pubmed/25501035 http://dx.doi.org/10.1038/nn.3898 |
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