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Structure-activity relationships of the intramolecular disulfide bonds in coprisin, a defensin from the dung beetle

Defensins, which are small cationic molecules produced by organisms as part of their innate immune response, share a common structural scaffold that is stabilized by three disulfide bridges. Coprisin is a 43-amino acid defensin-like peptide from Copris tripartitus. Here, we report the intramolecular...

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Detalles Bibliográficos
Autores principales: Lee, Jaeho, Lee, Daeun, Choi, Hyemin, Kim, Ha Hyung, Kim, Ho, Hwang, Jae Sam, Lee, Dong Gun, Kim, Jae Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281341/
https://www.ncbi.nlm.nih.gov/pubmed/24393527
http://dx.doi.org/10.5483/BMBRep.2014.47.11.262