Cargando…

Does progesterone show neuroprotective effects on traumatic brain injury through increasing phosphorylation of Akt in the hippocampus?

There are currently no federally approved neuroprotective agents to treat traumatic brain injury. Progesterone, a hydrophobic steroid hormone, has been shown in recent studies to exhibit neuroprotective effects in controlled cortical impact rat models. Akt is a protein kinase known to play a role in...

Descripción completa

Detalles Bibliográficos
Autores principales: Garling, Richard Justin, Watts, Lora Talley, Sprague, Shane, Fletcher, Lauren, Jimenez, David F., Digicaylioglu, Murat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281427/
https://www.ncbi.nlm.nih.gov/pubmed/25558238
http://dx.doi.org/10.4103/1673-5374.145355