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Does progesterone show neuroprotective effects on traumatic brain injury through increasing phosphorylation of Akt in the hippocampus?
There are currently no federally approved neuroprotective agents to treat traumatic brain injury. Progesterone, a hydrophobic steroid hormone, has been shown in recent studies to exhibit neuroprotective effects in controlled cortical impact rat models. Akt is a protein kinase known to play a role in...
Autores principales: | Garling, Richard Justin, Watts, Lora Talley, Sprague, Shane, Fletcher, Lauren, Jimenez, David F., Digicaylioglu, Murat |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281427/ https://www.ncbi.nlm.nih.gov/pubmed/25558238 http://dx.doi.org/10.4103/1673-5374.145355 |
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