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Initiation and maintenance of pluripotency gene expression in the absence of cohesin

Cohesin is implicated in establishing and maintaining pluripotency. Whether this is because of essential cohesin functions in the cell cycle or in gene regulation is unknown. Here we tested cohesin’s contribution to reprogramming in systems that reactivate the expression of pluripotency genes in the...

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Detalles Bibliográficos
Autores principales: Lavagnolli, Thais, Gupta, Preksha, Hörmanseder, Eva, Mira-Bontenbal, Hegias, Dharmalingam, Gopuraja, Carroll, Thomas, Gurdon, John B., Fisher, Amanda G., Merkenschlager, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281562/
https://www.ncbi.nlm.nih.gov/pubmed/25561493
http://dx.doi.org/10.1101/gad.251835.114