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Stably paused genes revealed through inhibition of transcription initiation by the TFIIH inhibitor triptolide
Transcription by RNA polymerase II (Pol II) in metazoans is regulated in several steps, including preinitiation complex (PIC) formation, initiation, Pol II escape, productive elongation, cotranscriptional RNA processing, and termination. Genome-wide studies have demonstrated that the phenomenon of p...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281563/ https://www.ncbi.nlm.nih.gov/pubmed/25561494 http://dx.doi.org/10.1101/gad.246173.114 |