Cargando…

ATPase-dependent auto-phosphorylation of the open condensin hinge diminishes DNA binding

Condensin, which contains two structural maintenance of chromosome (SMC) subunits and three regulatory non-SMC subunits, is essential for many chromosomal functions, including mitotic chromosome condensation and segregation. The ATPase domain of the SMC subunit comprises two termini connected by a l...

Descripción completa

Detalles Bibliográficos
Autores principales: Akai, Yuko, Kanai, Ryuta, Nakazawa, Norihiko, Ebe, Masahiro, Toyoshima, Chikashi, Yanagida, Mitsuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281712/
https://www.ncbi.nlm.nih.gov/pubmed/25520186
http://dx.doi.org/10.1098/rsob.140193