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ATPase-dependent auto-phosphorylation of the open condensin hinge diminishes DNA binding
Condensin, which contains two structural maintenance of chromosome (SMC) subunits and three regulatory non-SMC subunits, is essential for many chromosomal functions, including mitotic chromosome condensation and segregation. The ATPase domain of the SMC subunit comprises two termini connected by a l...
Autores principales: | Akai, Yuko, Kanai, Ryuta, Nakazawa, Norihiko, Ebe, Masahiro, Toyoshima, Chikashi, Yanagida, Mitsuhiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281712/ https://www.ncbi.nlm.nih.gov/pubmed/25520186 http://dx.doi.org/10.1098/rsob.140193 |
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