Architecture and dynamics of the autophagic phosphatidylinositol 3-kinase complex

The class III phosphatidylinositol 3-kinase complex I (PI3KC3-C1) that functions in early autophagy consists of the lipid kinase VPS34, the scaffolding protein VPS15, the tumor suppressor BECN1, and the autophagy-specific subunit ATG14. The structure of the ATG14-containing PI3KC3-C1 was determined...

Descripción completa

Detalles Bibliográficos
Autores principales: Baskaran, Sulochanadevi, Carlson, Lars-Anders, Stjepanovic, Goran, Young, Lindsey N, Kim, Do Jin, Grob, Patricia, Stanley, Robin E, Nogales, Eva, Hurley, James H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Biophysics and Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281882/
https://www.ncbi.nlm.nih.gov/pubmed/25490155
http://dx.doi.org/10.7554/eLife.05115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281882/
https://www.ncbi.nlm.nih.gov/pubmed/25490155
http://dx.doi.org/10.7554/eLife.05115

Ejemplares similares