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Architecture and dynamics of the autophagic phosphatidylinositol 3-kinase complex

The class III phosphatidylinositol 3-kinase complex I (PI3KC3-C1) that functions in early autophagy consists of the lipid kinase VPS34, the scaffolding protein VPS15, the tumor suppressor BECN1, and the autophagy-specific subunit ATG14. The structure of the ATG14-containing PI3KC3-C1 was determined...

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Detalles Bibliográficos
Autores principales:	Baskaran, Sulochanadevi, Carlson, Lars-Anders, Stjepanovic, Goran, Young, Lindsey N, Kim, Do Jin, Grob, Patricia, Stanley, Robin E, Nogales, Eva, Hurley, James H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2014
Materias:	Biophysics and Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281882/ https://www.ncbi.nlm.nih.gov/pubmed/25490155 http://dx.doi.org/10.7554/eLife.05115

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