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miR-93-directed down-regulation of DAB2 defines a novel oncogenic pathway in lung cancer

The disabled homolog 2 (DAB2) gene was recently identified as a tumor suppressor gene with its expression down-regulated in multiple cancer types. The role of DAB2 in lung tumorigenesis, however, is not fully characterized, and the mechanisms of DAB2 dysregulation in lung cancer are not defined. Her...

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Detalles Bibliográficos
Autores principales: Du, Liqin, Zhao, Zhenze, Ma, Xiuye, Hsiao, Tzu-Hung, Chen, Yidong, Young, Emily, Suraokar, Milind, Wistuba, Ignacio, Minna, John D., Pertsemlidis, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281941/
https://www.ncbi.nlm.nih.gov/pubmed/24037530
http://dx.doi.org/10.1038/onc.2013.381