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Progress and prospects for engineered T cell therapies

Proof-of-concept studies have demonstrated the therapeutic potential of engineered T cells. Transfer of recombinant antigen-specific T cell receptors (TCR) and chimaeric antigen receptors (CARs) against tumour and viral antigens are under investigation by multiple approaches, including viral- and no...

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Detalles Bibliográficos
Autores principales: Qasim, Waseem, Thrasher, Adrian J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282038/
https://www.ncbi.nlm.nih.gov/pubmed/24935654
http://dx.doi.org/10.1111/bjh.12981