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Biomarker-based treatment selection in early-stage rectal cancer to promote organ preservation

BACKGROUND: Total mesorectal excision (TME) remains commonplace for T1–2 rectal cancer owing to fear of undertreating a small proportion of patients with node-positive disease. Molecular stratification may predict cancer progression. It could be used to select patients for organ-preserving surgery i...

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Detalles Bibliográficos
Autores principales: Leong, K J, Beggs, A, James, J, Morton, D G, Matthews, G M, Bach, S P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282074/
https://www.ncbi.nlm.nih.gov/pubmed/25052224
http://dx.doi.org/10.1002/bjs.9571