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A novel unbiased counting method for the quantification of synapses in the mouse brain

BACKGROUND: The numerical density of synapses and their ultrastructural features are best assessed with electron microscopy. Counting is done within counting frames placed on a pair of sections (disector technique). But this requires that the thin sections are taken from comparable brain regions and...

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Detalles Bibliográficos
Autores principales: Reichmann, Florian, Painsipp, Evelin, Holzer, Peter, Kummer, Daniel, Bock, Elisabeth, Leitinger, Gerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier/North-Holland Biomedical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282307/
https://www.ncbi.nlm.nih.gov/pubmed/25445248
http://dx.doi.org/10.1016/j.jneumeth.2014.10.020