A Randomized Study of Lubiprostone for Opioid-Induced Constipation in Patients with Chronic Noncancer Pain

OBJECTIVE: To evaluate the efficacy and safety of oral lubiprostone for relieving symptoms of opioid-induced constipation (OIC) in patients with chronic noncancer pain. DESIGN: Prospective, randomized, double-blind, placebo-controlled trial. SETTING: Seventy-nine US and Canadian centers. SUBJECTS: P...

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Detalles Bibliográficos
Autores principales: Cryer, Byron, Katz, Seymour, Vallejo, Ricardo, Popescu, Anca, Ueno, Ryuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
General Section
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282321/
https://www.ncbi.nlm.nih.gov/pubmed/24716835
http://dx.doi.org/10.1111/pme.12437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282321/
https://www.ncbi.nlm.nih.gov/pubmed/24716835
http://dx.doi.org/10.1111/pme.12437

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