Cargando…

A Randomized Study of Lubiprostone for Opioid-Induced Constipation in Patients with Chronic Noncancer Pain

OBJECTIVE: To evaluate the efficacy and safety of oral lubiprostone for relieving symptoms of opioid-induced constipation (OIC) in patients with chronic noncancer pain. DESIGN: Prospective, randomized, double-blind, placebo-controlled trial. SETTING: Seventy-nine US and Canadian centers. SUBJECTS: P...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cryer, Byron, Katz, Seymour, Vallejo, Ricardo, Popescu, Anca, Ueno, Ryuji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	General Section
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282321/ https://www.ncbi.nlm.nih.gov/pubmed/24716835 http://dx.doi.org/10.1111/pme.12437

Ejemplares similares

A Randomized, Placebo-Controlled Trial of Lubiprostone for Opioid-Induced Constipation in Chronic Noncancer Pain
por: Jamal, M Mazen, et al.
Publicado: (2015)

Analysis of Nausea in Clinical Studies of Lubiprostone for the Treatment of Constipation Disorders
por: Cryer, Byron, et al.
Publicado: (2017)

Constipation in Elderly Patients with Noncancer Pain: Focus on Opioid-Induced Constipation
por: Chokhavatia, Sita, et al.
Publicado: (2016)

Safety of oral methylnaltrexone for opioid-induced constipation in patients with chronic noncancer pain
por: Rauck, Richard L, et al.
Publicado: (2018)

Update on the role of naldemedine in opioid-induced constipation in patients with chronic noncancer pain
por: BouSaba, Joelle, et al.
Publicado: (2022)

Satisfaction with Therapy Among Patients with Chronic Noncancer Pain with Opioid-Induced Constipation
por: LoCasale, Robert J., et al.
Publicado: (2016)

Lubiprostone: a novel treatment for chronic constipation
por: Lacy, Brian E, et al.
Publicado: (2008)

The Cost Effectiveness of Lubiprostone in Chronic Idiopathic Constipation
por: Pennington, Becky, et al.
Publicado: (2018)

Clinical Overview and Considerations for the Management of Opioid-induced Constipation in Patients With Chronic Noncancer Pain
por: Viscusi, Eugene R.
Publicado: (2019)

Effects of Lubiprostone, an Intestinal Secretagogue, on Electrolyte Homeostasis in Chronic Idiopathic and Opioid-induced Constipation
por: Rao, Satish S.C., et al.
Publicado: (2021)

Prioritizing a sequence of short-duration groups as the standardized pathway for chronic noncancer pain at an Australian tertiary multidisciplinary pain service: preliminary outcomes
por: Rajappa, Hema, et al.
Publicado: (2019)

Opioid-Induced Constipation and Bowel Dysfunction: A Clinical Guideline
por: Müller-Lissner, Stefan, et al.
Publicado: (2017)

Efficacy and Safety of Prucalopride in Patients with Chronic Noncancer Pain Suffering from Opioid-Induced Constipation
por: Sloots, Cornelius E. J., et al.
Publicado: (2010)

Long-Term Safety and Efficacy of Subcutaneous Methylnaltrexone in Patients with Opioid-Induced Constipation and Chronic Noncancer Pain: A Phase 3, Open-Label Trial
por: Webster, Lynn R., et al.
Publicado: (2017)

A Phase 2b, Randomized, Double-Blind Placebo-Controlled Study to Evaluate the Efficacy and Safety of Naldemedine for the Treatment of Opioid-Induced Constipation in Patients with Chronic Noncancer Pain
por: Webster, Lynn R, et al.
Publicado: (2017)

Analysis of opioid-mediated analgesia in Phase III studies of methylnaltrexone for opioid-induced constipation in patients with chronic noncancer pain
por: Webster, Lynn R, et al.
Publicado: (2015)

Peripherally acting μ-opioid receptor antagonists as treatment options for constipation in noncancer pain patients on chronic opioid therapy
por: Pergolizzi, Joseph V, et al.
Publicado: (2017)

Oral methylnaltrexone does not negatively impact analgesia in patients with opioid-induced constipation and chronic noncancer pain
por: Webster, Lynn R, et al.
Publicado: (2018)

A critical appraisal of lubiprostone in the treatment of chronic constipation in the elderly
por: Gras-Miralles, Beatriz, et al.
Publicado: (2013)

Factors associated with long-term efficacy of lubiprostone for chronic constipation
por: Morise, Takashi, et al.
Publicado: (2023)

Population Exposure‐Response Modeling of Naloxegol in Patients With Noncancer‐Related Pain and Opioid‐Induced Constipation
por: Al‐Huniti, N, et al.
Publicado: (2016)

Analysis of opioid-mediated analgesia in Phase III studies of methylnaltrexone for opioid-induced constipation in patients with chronic noncancer pain [Corrigendum]
Publicado: (2018)

European clinical practice recommendations on opioids for chronic noncancer pain – Part 1: Role of opioids in the management of chronic noncancer pain
por: Häuser, Winfried, et al.
Publicado: (2021)

Efficacy and Safety of Methylnaltrexone for Opioid-Induced Constipation in Patients With Chronic Noncancer Pain: A Placebo Crossover Analysis
por: Viscusi, Eugene R., et al.
Publicado: (2016)

Naldemedine in Japanese patients with opioid-induced constipation and chronic noncancer pain: open-label Phase III studies
por: Saito, Yoji, et al.
Publicado: (2018)

Long-Term Safety and Effectiveness of Lubiprostone, a Chloride Channel (ClC-2) Activator, in Patients with Chronic Idiopathic Constipation
por: Lembo, Anthony J., et al.
Publicado: (2011)

Efficacy and safety of linaclotide for opioid-induced constipation in patients with chronic noncancer pain syndromes from a phase 2 randomized study
por: Brenner, Darren M., et al.
Publicado: (2020)

Lubiprostone for the Treatment of Adult Women with Irritable Bowel Syndrome with Constipation
por: Soubra, Mahmoud, et al.
Publicado: (2012)

Lubiprostone for the Treatment of Clozapine-Induced Constipation: A Case Series
por: Torrico, Tyler J, et al.
Publicado: (2022)

Spotlight on naldemedine in the treatment of opioid-induced constipation in adult patients with chronic noncancer pain: design, development, and place in therapy
por: Stern, Emily K, et al.
Publicado: (2018)

Opioid Pharmacotherapy for Chronic Noncancer Pain: The American Experience
por: Chapman, C. Richard
Publicado: (2013)

Effects of baseline abdominal pain and bloating on response to lubiprostone in patients with irritable bowel syndrome with constipation
por: Chang, L., et al.
Publicado: (2016)

Oral methylnaltrexone is efficacious and well tolerated for the treatment of opioid-induced constipation in patients with chronic noncancer pain receiving concomitant methadone
por: Webster, Lynn R, et al.
Publicado: (2018)

Capsule and Sprinkle Formulations of Lubiprostone Are Not Biologically Similar in Patients with Functional Constipation
por: Adams, Atoya, et al.
Publicado: (2021)

Chronic Noncancer Pain and Opioid Addiction: Diagnostic and Management Challenges
por: Kathiresan, Preethy, et al.
Publicado: (2020)

Influence of opioid-related side effects on disability, mood, and opioid misuse risk among patients with chronic pain in primary care
por: Jamison, Robert N., et al.
Publicado: (2017)

Incidence and Health Related Quality of Life of Opioid-Induced Constipation in Chronic Noncancer Pain Patients: A Prospective Multicentre Cohort Study
por: Veiga, Dalila R., et al.
Publicado: (2018)

Onset of action of naldemedine in the treatment of opioid-induced constipation in patients with chronic noncancer pain: results from 2 randomized, placebo-controlled, phase 3 trials
por: Wild, James, et al.
Publicado: (2019)

Long-term Safety and Tolerability of NKTR-181 in Patients with Moderate to Severe Chronic Low Back Pain or Chronic Noncancer Pain: A Phase 3 Multicenter, Open-Label, 52-Week Study (SUMMIT-08 LTS)
por: Gudin, Jeffrey, et al.
Publicado: (2020)

Risk Assessment of Opioid Misuse in Italian Patients with Chronic Noncancer Pain
por: Ferrari, Renata, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_38l1m5b6gcjm3ujvr5m8hfhgoc