Empirical Bayes estimation of the selected treatment mean for two-stage drop-the-loser trials: a meta-analytic approach

Point estimation for the selected treatment in a two-stage drop-the-loser trial is not straightforward because a substantial bias can be induced in the standard maximum likelihood estimate (MLE) through the first stage selection process. Research has generally focused on alternative estimation strat...

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Detalles Bibliográficos
Autores principales: Bowden, Jack, Brannath, Werner, Glimm, Ekkehard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282323/
https://www.ncbi.nlm.nih.gov/pubmed/23873666
http://dx.doi.org/10.1002/sim.5920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282323/
https://www.ncbi.nlm.nih.gov/pubmed/23873666
http://dx.doi.org/10.1002/sim.5920

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