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Empirical Bayes estimation of the selected treatment mean for two-stage drop-the-loser trials: a meta-analytic approach
Point estimation for the selected treatment in a two-stage drop-the-loser trial is not straightforward because a substantial bias can be induced in the standard maximum likelihood estimate (MLE) through the first stage selection process. Research has generally focused on alternative estimation strat...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BlackWell Publishing Ltd
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282323/ https://www.ncbi.nlm.nih.gov/pubmed/23873666 http://dx.doi.org/10.1002/sim.5920 |