A chronic oral reference dose for hexavalent chromium-induced intestinal cancer†

High concentrations of hexavalent chromium [Cr(VI)] in drinking water induce villous cytotoxicity and compensatory crypt hyperplasia in the small intestines of mice (but not rats). Lifetime exposure to such cytotoxic concentrations increases intestinal neoplasms in mice, suggesting that the mode of...

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Detalles Bibliográficos
Autores principales: Thompson, Chad M, Kirman, Christopher R, Proctor, Deborah M, Haws, Laurie C, Suh, Mina, Hays, Sean M, Hixon, J Gregory, Harris, Mark A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282340/
https://www.ncbi.nlm.nih.gov/pubmed/23943231
http://dx.doi.org/10.1002/jat.2907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282340/
https://www.ncbi.nlm.nih.gov/pubmed/23943231
http://dx.doi.org/10.1002/jat.2907

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