Netupitant PET imaging and ADME studies in humans

Netupitant is a new, selective NK(1) receptor antagonist under development for the prevention of chemotherapy-induced nausea and vomiting. Two studies were conducted to evaluate the brain receptor occupancy (RO) and disposition (ADME) of netupitant in humans. Positron emission tomography (PET) imagi...

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Detalles Bibliográficos
Autores principales: Spinelli, Tulla, Calcagnile, Selma, Giuliano, Claudio, Rossi, Giorgia, Lanzarotti, Corinna, Mair, Stuart, Stevens, Lloyd, Nisbet, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282341/
https://www.ncbi.nlm.nih.gov/pubmed/24122871
http://dx.doi.org/10.1002/jcph.198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282341/
https://www.ncbi.nlm.nih.gov/pubmed/24122871
http://dx.doi.org/10.1002/jcph.198

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