Calcium-sensing receptor silencing in colorectal cancer is associated with promoter hypermethylation and loss of acetylation on histone 3

The calcium-sensing receptor (CaSR) is suggested to mediate the antiproliferative effects of calcium in colon. However, in colorectal cancer (CRC) the expression of the CaSR is silenced and the underlying mechanisms leading to its loss are poorly understood. We investigated whether loss of the CaSR...

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Detalles Bibliográficos
Autores principales: Fetahu, Irfete S, Höbaus, Julia, Aggarwal, Abhishek, Hummel, Doris M, Tennakoon, Samawansha, Mesteri, Ildiko, Baumgartner-Parzer, Sabina, Kállay, Enikő
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Carcinogenesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282356/
https://www.ncbi.nlm.nih.gov/pubmed/24691920
http://dx.doi.org/10.1002/ijc.28856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282356/
https://www.ncbi.nlm.nih.gov/pubmed/24691920
http://dx.doi.org/10.1002/ijc.28856

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