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The Activation and Inactivation of Mature CD4 T cells: A Case for Peripheral Self–Nonself Discrimination
The establishment of central tolerance to most self-antigens results in a repertoire of mature peripheral lymphocytes specific for foreign and peripheral self-antigens. The framework that single, mature lymphocytes are inactivated by antigen, whereas their activation requires lymphocyte cooperation,...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BlackWell Publishing Ltd
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282366/ https://www.ncbi.nlm.nih.gov/pubmed/24684567 http://dx.doi.org/10.1111/sji.12173 |