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Comparing the Efficacy of SNP Filtering Methods for Identifying a Single Causal SNP in a Known Association Region
Genome-wide association studies have successfully identified associations between common diseases and a large number of single nucleotide polymorphisms (SNPs) across the genome. We investigate the effectiveness of several statistics, including p-values, likelihoods, genetic map distance and linkage...
Hauptverfasser: | , , |
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Format: | Online Artikel Text |
Sprache: | English |
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BlackWell Publishing Ltd
2014
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Online Zugang: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282378/ https://www.ncbi.nlm.nih.gov/pubmed/24205929 http://dx.doi.org/10.1111/ahg.12043 |