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An optimized Protocol for Human M2 Macrophages using M-CSF and IL-4/IL-10/TGF-β Yields a Dominant Immunosuppressive Phenotype

Monocytes are highly abundant circulatory effector cells and play a vital role in driving or resolving inflammatory processes depending on their activation phenotype. We investigated and compared a panel of polarization protocols of blood-derived monocytes to achieve a stable, optimal and effective...

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Detalles Bibliográficos
Autores principales: Mia, S, Warnecke, A, Zhang, X-M, Malmström, V, Harris, R A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282403/
https://www.ncbi.nlm.nih.gov/pubmed/24521472
http://dx.doi.org/10.1111/sji.12162